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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb46741834166d51b79bd1433031e2f3c28bf6f63b5bd03bac1160e8daa3fa19' 
  AND token = 'ArT4Vs6F8Yx0VBbbx8qKDYLnmDWvKnkXclhcz/ZHhXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}