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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e87d2a3e38f25428bf01a1e08170d3ca8a2f8ae2cd1ade31cdb151573f3b37c4' 
  AND token = 'G42GqIe8r2XQGWg2bdUgN5b5lZRAjr8RxxI5tcakzgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}