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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d02f451454bcb024aa8fb8c7e5bb079d8449a9dfbdbbeea7ee0a7496481856' 
  AND token = '/U6S3zCrLj0okNR/a9FZ+mIH4fwEiqHXhBh5AeKjMX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}