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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563b185a84654c7c8c799058880b30eacd2103216e551fdc2f8ebda2e0de002d' 
  AND token = 'iXEpsYFNSO/MVwFpsg/o8b1Ioq4zYCwb+nzs0r4X6UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}