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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f578b0ecece480f75e5fca68e833c16e74c0fdda8bcbd8760f27189fb62a781' 
  AND token = 'G/LE2o0erCZQgCIutPWXsjVnU0DXuS/PSFyNOY8lPiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}