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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19e8f56164b5399a1285be48307f8436f37f6f3182908139f9a549033138304c' 
  AND token = '4/bbqQq86I+xA3wOwFSXmcJUMOcrFtQIqZcXZAJxURk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}