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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8bb0a770a8808d9843599b685ddc0fa8b3aa2f27e282d3f9c68e3e96814d55' 
  AND token = '8ZW9XefJ4SJ92UKBwtwSKcOrN7ODLCopTiWb6ZmbYAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}