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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a74215021fe19d1dbb45a3a5df18e959284d3ea76790910e683d43e8964c4aea' 
  AND token = 'epC3gKE+JK8+QeqI8wfgW2lfQLJDFkNj05f/8/uhhfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}