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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb784fce750682e5589c44a03fc53a41728d3cdff1e59fd5ae5d543f31c6a147' 
  AND token = 'HdHVcALvu7yT2xd9+0+105HXHKIppYznfQdGdc72WWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}