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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c26bf62690fde4a0d0affbae020fd6742003c00981fb3a105eab36318dca05' 
  AND token = 'K9jAF941fim29t6P6Du6CIKTweq2NZ+kGmUwx8e2Rdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}