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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d3a8fd23cb68e32cfbb23904f26eed0d0084d263eceb160a69d0410d77a9c3' 
  AND token = 'tgkvqA+bfcS/y/1K7L6i3flrT4KSyMfRqx9zLXuy81o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}