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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed64b6388cb72ed860ad21ec9f7ce7c4e4674aaa06809b4be1db7bfa6e9014f' 
  AND token = 'dmDiTWP0d6aUlhJEJEuCd2dYRrHChS6KHQoHkELBkm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}