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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3afc282f7317004893cc16b7ebf43b12b1faeb775f6ba39fbe08a1c6b8c5bc46' 
  AND token = 'wIg2M+hIRc/9UHs66pfTfG6cEX4vBXW2gSaabv6hOhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}