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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1e6d67cac3710dc827f695440b1bf58e7b7f757b2115a13efe28c85b6815a9e' 
  AND token = 'uSAyXyFxjF5U/hkQkJaBcmlkD9cXP5rKxmMUocikFU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}