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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c7651fefb3b0021fd41b5a74b009b22887659db58b6a926ca05f5e4cb65589' 
  AND token = 'OYgL+W9jAXNihQisvHHPoHpeQpSy9yL130hQneaYLQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}