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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b4b39eedb7d6b695ace1ead5cb2ada311b14acda00e461f4e5dbb9650c1164' 
  AND token = '+Pnepb+n3cV4eoPS4JaAidh0ubWT/pnLUDYJM8shDcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}