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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d23fb9338b9c400f4948173947769a48e26a86dd186ddc2c7482061bfce14f' 
  AND token = 'SgCoOJ6q6No2VoxCm6ghEcvGdOVKSC3b3uHByJ6jKjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}