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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d2f5034cd9e862bf6705f184f305502944d1cf5d8b3b049f0863620f2bbea08' 
  AND token = 'uzEoh2JuTpYkAyGuNWnnLEq39fNiL/7b3pJGj5vwEzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}