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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10c5fbbf477ec18d5d4481186796137fbcc70faed00327eef125a457669aaa86' 
  AND token = 'MYX+7yD7pfSOYiSA0WE6AwdJTH5+VHqQFu5U/rM5QnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}