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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df0c8242b32c622c6800a76562b6949dc43eb93dc7f6bac6985c3e2fa23676e' 
  AND token = 'kHFZ1LcLnFzCa6KYkz5fG9gOqc3m5ZAxBX78yYAPYJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}