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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6296a2b59cf1d273541e73134992867b42e92c1c3fbf5e7a1701ca28672860b0' 
  AND token = '7wf6TS2VxEf8nWLoWc12WhKMzJ0BDmJDzuLj+EL0BAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}