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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b402121f31adc3c022ec9505772851b4cd74c1a49f1933da5dbe35bbe3280e88' 
  AND token = '+W2rSzNu9qtDXfAxKyoFemfZzG+xkSYo/6rmkQC1+mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}