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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37587554312015be3a0666130a60b7ff6824a4c17d3e2f26d7e3c4d2be5b2069' 
  AND token = 'aXIrsMwXo3X+wPpust3EgNop0ZK4qS9S1/fLc2Vk588=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}