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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfd278ff555f9cf5cd11fe526983857cbca7c046d0183737f0ef2ceac1db1c12' 
  AND token = 'R0H0VPNOD4sKoDgJyHL+NEtp6ye0R0ZYufkj0Ttuds8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00112

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}