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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59dd19077737b42d5ec832743d256a0b1a0979ff2dd6fb956ace39ab914a64d1' 
  AND token = 'kgs7hAf7ChauBTEHC0SUf8IEH3Wc7hYVwqqD8bHUyAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}