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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2378e84c4d247f61a9e1b94b12a49c5bd4d6cf2269e35530e9e37965198c5d8' 
  AND token = 'uydLQ9ca9Hvyq052YGx2vC9GoYL5gz2kzmv5P9aZ5o4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}