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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb3dd0ab9b2dae079f31eba0a199a56de874f9f6bd4be7a77acf22dde790a261' 
  AND token = 'sH4RY8tnuSGKMjkV9ZcnXXauvOdW5XEqrOuxLBdOHLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}