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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e28d39237d8fc067d7a05f1af2f5fe05866c865b0e9735b8902072ace509bf' 
  AND token = 'gX9OIusyTAkIjL9vGXpgDbtVlMw2jJ0WxvSRvrXMx2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}