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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a28ef7de9a78bdba47612d62a34d6553e1c03e9bf24583d69e0b61627f82c0b' 
  AND token = 'aIPNHy7bIhBeHUDe2/RL93GK2f4zBfuyTOJPZSCGEqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}