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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d85c181d96fdffecf398c721d7b464725d3cd80d051876295e1dcf0276ce43' 
  AND token = '/JE+lBko9SZLmspSS69uKo2azPsKIpZEkME7E4Ah1Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}