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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1506c2fc0d81d94ecb32c5aa0552b47bf64417e94b9aaa56a486a09579539f' 
  AND token = 'GMuXi+g1QrmxMsX+1yW867b6kL9S8ABvX6UYYOzS6mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}