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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f224631991e359ac4de0a63731cadfa36891b3c581144bc18afe63ec357e780d' 
  AND token = 'e4ej/Dk9dCa1YX6Kh25rJnOSXRUybcRYsQKolORBXY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}