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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46ac0157f83a713579f5565d06ec60af89b34c8cf8a4f29d9346fa4feb2120c' 
  AND token = 'qaO6suksZghmEw0i6ZLIrLmuiDXurDIbxHbaoPd5VWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}