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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14729a6e39d4cf2b06b6911e9bde74f8ccd1bfb9246863de80bd97a55492e18f' 
  AND token = '6xE9rJgQrvm/7/giDaf82WgRzKYm1Fd+u9rDNtQtXKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}