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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '075034cd8c8c819b02e3dea8dfc34360227c03b95f0fa4a5a08fea38a5d5f606' 
  AND token = '2sONk0rAEs5p6pvyYRCSxhQ81LZ1eWkXjpqlmY5AKPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}