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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '779c198f7e1ca6a5b79d6f9a6aee1ab57a72a765a80730e7125531ae2eb5c039' 
  AND token = 'u2Z5R+uQSfZSxoGDsbxOYBchoM3uv7OBHWXNqhaw4Fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}