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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5525e5bc62f5ff48edc62245409b88e0151cfa89561d0de51b5b1d83451bc466' 
  AND token = 'lwUPcH/cO/IlJD24Ko/FKQFWp1Z68wRRDVTNhT3uJrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}