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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bf8216fd925418897b8a1cd1520bd35d22aed5faaff0b1cd6e07cdd3f8bfcdc' 
  AND token = 'uxu2JrKJAAXLfjkuN3XLBK6NOg1IKdxr9kpQzCHZCWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}