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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76b8e697026d6d4f35c28f203a483879c9a0d06c7c21d422174bc0de6d407f93' 
  AND token = 'ufVz9Qhhz/iczh1iwCNj/X/6gDF3SdGo8I5Udo3lxLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}