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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a4f9216d891fb42b1e87010f0b8272f6a9aad56ce659e482faeefebee9c486' 
  AND token = 'aN4GeChA4DYRzBSooKV+y7LR7M5P3K5z5KsGYSfv/u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}