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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764fe46c3090162b405a8537db6c08fcfee875058d071c5a7a4ad61edeff428c' 
  AND token = 'OD03nio2uh+ZgUkXWnQyWT1bab62Y6cnEGL3M7iNvgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}