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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb5cf4f667b2829c8e8b5a06b3b1f99e9b6873e53f02c4b7be25e693148e47d' 
  AND token = 'wyxthOYte2/LtO1Kn4oJTrMD9Zsw9KQcUkxGEmzhTDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}