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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf1edd9ef0178a36bb207fe82f5e38ef81f45e78aa77172fd90c91f3260ab8f9' 
  AND token = 'P4wH9DqtJM3HFE2qPIId7zod5+pAOXsX31/lCToFsLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}