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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249d9cae416da8bffb0e055b5ecdbc0033edb8e1f81a60a88b34b6f6c8ba07a6' 
  AND token = 'UcZzgHSRnK4LrJoCt6n8hqqN3fyLV3ueE7oKmpgD+Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}