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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89e2dd24898eff6758933b4614bc1209a2c906f34769d4968e728704d5612d57' 
  AND token = 'XOOt49TPBb2SZcJWKdFr7oNCXmnWH1EDg/K8aBKXY/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}