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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e7f522fa91dccd53239f763c4dbae26827bd61bcd5c1333852a33d7e12b6c1' 
  AND token = 'lkZStq3K3o33p/AwvoqMAVMfVIXoSFuqTyNO6/Rdmhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}