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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '191d48ae12c3a921b12a51752bc056bf70da1a89af1aa49e30f073691b1be020' 
  AND token = '1E/kk9U7VSMi8xqikfgbEv5z4e8AjssdIKUpbpxx2E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}