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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34fe1e8c98a0a3708a07c335626a3ab319fe82036ffc568be4f1b80396038e72' 
  AND token = 'ZPVUqC2xYaI/4yvGMjRFlyfHWltS52ZtRjV1UwXXPi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}