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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641d2fdae02ec1bdafb86e593f7d78c7c27a3ce78a4cb697ea90680856eb8674' 
  AND token = 'ZFoO5k+rLjq8mANOYOUgRrIBHjdUdgfHot2gZSGuHP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}