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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b52b79767e39713c633e9cfa8127f8abe6b37f9165f6475515d4afe982c088d8' 
  AND token = 'qv4fUw5bwIx/8DUDZr/e47Euo/E/8lHLMMixSdIvXVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}